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About TTXA comprehensive enterprise specializing in the R&D, production, and sales of feed additives.
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ProductsWe specialize in providing high-quality feed additive solutions for farmed animals, including livestock, poultry, aquaculture, and ruminants.
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TechnologyWe consistently adhere to technological innovation as the core driving force and are committed to promoting technological advancement in the industry.
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Contact UsWe look forward to collaborating with more partners to jointly promote the sustainable development of the aquaculture industry and contribute to global food security.
Scientific Use of Mycotoxin Detoxifiers: A Key Step in Safeguarding Feed Safety
Release time:
2025-04-24
In modern animal husbandry, feed safety is a critical component for ensuring animal health and enhancing farming efficiency. Mycotoxin contamination, often referred to as the “silent killer” in the feed industry, not only leads to stunted animal growth and weakened immune systems but can also pose a threat to human health through the food chain. As an essential tool for controlling mycotoxins, the proper use of mycotoxin binders has become an indispensable skill for both feed manufacturers and livestock farmers.
One, Mold removal agent Principle of Operation and Classification
Mycotoxin decontaminants primarily reduce the hazards of mycotoxins through mechanisms such as physical adsorption, biodegradation, or chemical neutralization. Based on their mechanisms of action, they can be categorized into three types:
1. Adsorptive mycotoxin adsorbents: Primarily composed of montmorillonite, activated carbon, and other similar materials, these adsorbents utilize their porous structure to adsorb polar toxins such as aflatoxins;
2. Biodegradable mycotoxin detoxifiers: These utilize enzyme preparations or probiotics to break down toxin molecules (such as zearalenone).
3. Composite mycotoxin decontaminant: Combines adsorption, degradation, and immunomodulatory functions, making it suitable for scenarios involving complex mycotoxin contamination.
II. Five Key Points for the Correct Use of Mold-Removing Agents
1. Accurate detection, targeted treatment.
Before using a mycotoxin decontaminant, it is necessary to detect the types and levels of mycotoxins in the feed using an ELISA kit or high-performance liquid chromatography (HPLC). For example, corn raw materials are prone to contamination by aflatoxins, whereas wheat byproducts require particular attention to deoxynivalenol.
2. Add scientifically according to dosage
The dosage of mycotoxin adsorbents should be adjusted dynamically based on the concentration of toxins and the type of feed. Taking montmorillonite as an example, the conventional addition rate is 1–2 kg per ton of feed. However, if the level of aflatoxin B1 exceeds the standard (>50 ppb), the dosage can be increased to 3 kg per ton, while also supplementing vitamin A to mitigate issues related to nutrient adsorption.
3. Ensuring uniform mixing for effective results
When using a vertical mixer, make sure the mycotoxin decontaminant is thoroughly mixed with the feed for at least 10 minutes. It is recommended to first pre-mix it with a small amount of carrier material and then gradually increase the mixing ratio step by step, thereby avoiding local ineffectiveness caused by layering.
4. Pay attention to the timing and frequency of use.
During periods of high temperature and high humidity or when raw materials are stored for more than 30 days, the dosage of the mold inhibitor should be increased by 20%. After continuously using the same type of mold inhibitor for over 3 months, it is recommended to switch to a different formulation to prevent the development of fungal resistance.
5. Integrate end-to-end management measures
Mycotoxin decontaminants must be used in conjunction with measures such as drying raw materials (moisture content <14%) and ensuring well-ventilated storage conditions (relative humidity <65%). For feed that has already become moldy, mycotoxin decontaminants can only reduce the risk but cannot replace proper disposal.
III. Common Misconceptions and Risk Warnings in Usage
Misconception 1: Judging effectiveness based on color changes
Some farmers mistakenly believe that a darker color of mycotoxin adsorbents indicates enhanced toxin adsorption. In reality, the color change is related to the composition of the raw materials and requires professional testing to verify its effectiveness.
Misconception 2: Blindly relying on a single product
Combined contamination by multiple toxins requires a “adsorption plus degradation” approach. For example, in cases where ochratoxin and zearalenone coexist, it is recommended to use montmorillonite in combination with glucose oxidase.
Latest experiment
Broiler Glucose Oxidase Experiment
One-day-old Ross 308 broiler chickens were selected, with a total of 4 chicken houses, each housing 11,000 birds. The birds were randomly divided into a control group and a treatment group, with 2 chicken houses assigned to each group. The control group was fed a commercial diet supplemented with Changle (allicin and oregano phenol) at 100 mL/ton, while the treatment group was fed a commercial diet supplemented with glucose oxidase at 100 U/L. During the trial period, birds had free access to feed and water. The trial lasted for 42 days. The experimental diet consisted of corn, soybean meal, wheat, cottonseed meal, DDGS, peanut meal, duck fat, and premixes, among other ingredients; nutritional parameters are shown in Table 1.
Lactic Acid Bacteria Experiment
Effect of Lactic Acid Bacteria on Broiler Diarrhea: A Raising Experiment Experimental Site: Jiyang Zheng* Animal Husbandry Farm Experiment Period: August 31, 2015 – September 4, 2015 Experimental Subjects: 30-day-old broilers Experimental Design: Control Group: Normal feeding + normal drinking water Experimental Group: Normal feeding + normal drinking water + lactic acid bacteria (liquid)
Piglet Fruit Milk Flavor Experiment
Twenty 28-day-old weaned piglets of the Duroc × Landrace × Large White crossbreed, with similar body weights and in good health, were selected for the trial. They were randomly divided into two treatment groups: a control group and a test group. The control group was fed a basal diet, while the test group was fed a basal diet supplemented with 600 g/t of fruit-milk flavoring. Each group consisted of five replicates, with two piglets per replicate. During the trial period, the pigs had free access to feed and water, and the trial lasted for 28 days.
In this trial, 120 healthy, growing pigs of similar body condition, weighing 80 ± 10 kg, were randomly divided into a control group, an antibiotic group, and an essential oil group. The specific feeding design is shown in Table 1. Each group consisted of 4 replicates, with 10 pigs per replicate. The trial duration was 29 days. The experimental diet was formulated according to the nutritional requirements outlined in NRC (2012). During the trial, pigs had free access to feed and water, and were subjected to routine husbandry management and vaccination protocols. Body weights at the beginning and end of the trial, as well as feed intake, were recorded. At the end of the trial, fresh fecal samples were collected from each pig, placed into sterile 10 ml centrifuge tubes, and stored at -80℃.
Tian Yikang replaces chlortetracycline in the ROSS-308 trial.
This experiment employed a single-factor experimental design. A total of 6,000 Ross-308 broiler chickens, aged 1 day and with roughly similar body weights and good health conditions, were randomly selected and divided into three treatment groups, with five replicates per group, each replicate consisting of 400 chickens. The control group was fed a basal diet based on corn and soybean meal. The experimental group 1, the antibiotic group, had 50 g/t of a 15% chlortetracycline premix added to the basal diet. The experimental group 2, the Tianyikang addition group, had 1,500 g/t of Tianyikang added to the basal diet. The entire experiment lasted for 42 days.
Since 1998, focused on animal feed intake and health.
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